The star of the funniest TV show you've never seen

She's made a career for herself, channeling misfits and quick wits in box-office hits like Mean Girls. Now she's back to battle a different type of evil altogether, in the highly anticipated J.J. Abrams-produced monster smash.

She's in a new monster smash produced by a TV exec who revels in fake names and lost islands. It's poised to become the biggest studio feature of 2008, and still, the former freak (and geek) can't seem to catch a break.